The Psychology of Distance: Isolation, Confinement, and Psychological Sustainability in Space Analogs and Long-Duration Missions
DOI:
https://doi.org/10.65166/1z6bd817Keywords:
isolated and confined environments, long-duration spaceflight, psychological sustainability, cognitive performance, crew cohesion, behavioral health monitoringAbstract
Long-duration missions beyond low-Earth orbit expose crews to prolonged isolation, spatial confinement, environmental monotony, communication delays, disrupted circadian rhythms, and sustained interpersonal demands. These conditions may compromise psychological wellbeing, cognitive performance, team cohesion, and operational decision-making. This structured literature review synthesizes evidence from Antarctic overwinter stations, submarine deployments, ground-based simulations such as MARS-500 and HI-SEAS, NASA’s Crew Health and Performance Exploration Analog program, and relevant human-factors research. The review examines five interrelated domains: individual affective and cognitive effects; team dynamics and group cohesion; behavioral health monitoring; habitat and schedule design; and cultural, compositional, and individual-difference factors. The synthesis identifies an interacting architecture of psychological risk operating at individual, group, and systemic levels. Evidence further suggests that psychological vulnerability may intensify during middle-to-late mission phases, although temporal patterns vary across missions and analog environments. A three-tier framework distinguishes operationally supported countermeasures from preliminarily supported interventions and theoretically grounded proposals requiring further validation. Structured schedules, protected rest periods, circadian lighting, private personal space, and sustained communication with Earth currently have the strongest operational support. Cross-cultural preparation, competency-based selection, autonomous monitoring, and immersive technologies remain promising but incompletely validated. The review concludes that psychological sustainability cannot be secured through crew selection alone. It must be incorporated into habitat architecture, operational scheduling, monitoring governance, crew preparation, and mission-support systems. The findings also inform terrestrial operations conducted in isolated, confined, and extreme environments.
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Abeln, V., Fomina, E., Popova, J. A., Braunsmann, L., Koschate, J., Möller, F., Fedyay, S. O., Vassilieva, G. Y., Schneider, S., Strüder, H. K., & Klein, T. (2022). Chronic, acute and protocol-dependent effects of exercise on psycho-physiological health during long-term isolation and confinement. BMC Neuroscience, 23, Article 41. https://doi.org/10.1186/s12868-022-00723-x
Acien, A., Morales, A., Vera-Rodríguez, R., Fierrez, J., Mondesire-Crump, I., & Arroyo-Gallego, T. (2022). Detection of mental fatigue in the general population: Feasibility study of keystroke dynamics as a real-world biomarker. JMIR Biomedical Engineering, 7(2), e41003. https://doi.org/10.2196/41003
Alfano, C. A., Bower, J. L., Connaboy, C., Agha, N. H., Baker, F. L., Smith, K. A., So, C., & Simpson, R. J. (2021). Mental health, physical symptoms and biomarkers of stress during prolonged exposure to Antarctica’s extreme environment. Acta Astronautica, 181, 405–413. https://doi.org/10.1016/j.actaastro.2021.01.051
Basner, M., Dinges, D. F., Mollicone, D. J., Savelev, I., Ecker, A. J., Di Antonio, A., Jones, C., Hyder, E. C., Kan, K., Morukov, B. V., & Sutton, J. P. (2014). Psychological and behavioral changes during confinement in a 520-day simulated interplanetary mission to Mars. PLOS ONE, 9(3), e93298. https://doi.org/10.1371/journal.pone.0093298
Bell, S. T., Brown, S. G., & Mitchell, T. (2019). What we know about team dynamics for long-distance space missions: A systematic review of analog research. Frontiers in Psychology, 10, Article 811. https://doi.org/10.3389/fpsyg.2019.00811
Bhatt, P., Sethi, A., Tasgaonkar, V., Shroff, J., Pendharkar, I., Desai, A., Sinha, P., Deshpande, A., Joshi, G., Rahate, A., Jain, P., Walambe, R., Kotecha, K., & Jain, N. K. (2023). Machine learning for cognitive behavioral analysis: Datasets, methods, paradigms, and research directions. Brain Informatics, 10, Article 18. https://doi.org/10.1186/s40708-023-00196-6
Browning, M. H. E. M., Mimnaugh, K. J., van Riper, C. J., Laurent, H. K., & LaValle, S. M. (2020a). Can simulated nature support mental health? Comparing short, single doses of 360-degree nature videos in virtual reality with the outdoors. Frontiers in Psychology, 10, Article 2667. https://doi.org/10.3389/fpsyg.2019.02667
Browning, M. H. E. M., Shipley, N. J., McAnirlin, O., Becker, D. A., Yu, C.-P., Hartig, T., & Dzhambov, A. M. (2020b). An actual natural setting improves mood better than its virtual counterpart: A meta-analysis of experimental data. Frontiers in Psychology, 11, Article 2200. https://doi.org/10.3389/fpsyg.2020.02200
Browning, M. H. E. M., Shin, S., Drong, G., McAnirlin, O., Gagnon, R. J., Ranganathan, S., Sindelar, K., Hoptman, D., Bratman, G. N., Yuan, S., Prabhu, V. G., & Heller, W. (2023). Daily exposure to virtual nature reduces symptoms of anxiety in college students. Scientific Reports, 13, Article 1239. https://doi.org/10.1038/s41598-023-28070-9
Chapman, J., Roberts, J. A., Nguyen, V. T., & Breakspear, M. (2017). Quantification of free-living activity patterns using accelerometry in adults with mental illness. Scientific Reports, 7, Article 43174. https://doi.org/10.1038/srep43174
de Zambotti, M., Cellini, N., Goldstone, A., Colrain, I. M., & Baker, F. C. (2019). Wearable sleep technology in clinical and research settings. Medicine & Science in Sports & Exercise, 51(7), 1538–1557. https://doi.org/10.1249/MSS.0000000000001947
Fischer, U., & Mosier, K. L. (2015). Communication protocols to support collaboration in distributed teams under asynchronous conditions. Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 59(1), 1–5. https://doi.org/10.1177/1541931215591001
Gushin, V., Ryumin, O. O., Karpova, O. I., Rozanov, I. A., Shved, D. M., & Yusupova, A. (2021). Prospects for psychological support in interplanetary expeditions. Frontiers in Physiology, 12, Article 750414. https://doi.org/10.3389/fphys.2021.750414
Hong, L., & Page, S. E. (2004). Groups of diverse problem solvers can outperform groups of high-ability problem solvers. Proceedings of the National Academy of Sciences of the United States of America, 101(46), 16385–16389. https://doi.org/10.1073/pnas.0403723101
Johnson, J. C., Boster, J. S., & Palinkas, L. A. (2003). Social roles and the evolution of networks in extreme and isolated environments. The Journal of Mathematical Sociology, 27(2–3), 89–121. https://doi.org/10.1080/00222500305890
Kanas, N. (1998). Psychosocial issues affecting crews during long-duration international space missions. Acta Astronautica, 42(1–8), 339–361. https://doi.org/10.1016/S0094-5765(98)00130-1
Kanas, N. (2005). Interpersonal issues in space: Shuttle/Mir and beyond. Aviation, Space, and Environmental Medicine, 76(6, Suppl.), B126–B134.
Kanas, N., Salnitskiy, V., Weiss, D. S., Grund, E. M., Gushin, V., Kozerenko, O., Sled, A., Bostrom, A., & Marmar, C. R. (2001). Crewmember and ground personnel interactions over time during Shuttle/Mir space missions. Aviation, Space, and Environmental Medicine, 72(5), 453–461.
Käosaar, A., Marques-Quinteiro, P., & Burke, S. (2022). Fantastic teams and where to find them: Understanding team processes in space and analog environments through the IMOI framework. Team Performance Management: An International Journal, 28(3–4), 109–124. https://doi.org/10.1108/TPM-02-2021-0012
Kappen, M., Vanhollebeke, G., Van Der Donckt, J., Van Hoecke, S., & Vanderhasselt, M.-A. (2024). Acoustic and prosodic speech features reflect physiological stress but not isolated negative affect: A multi-paradigm study on psychosocial stressors. Scientific Reports, 14, Article 5515. https://doi.org/10.1038/s41598-024-55550-3
Kawasaki, A., Wisniewski, S., Healey, B., Pattyn, N., Kunz, D., Basner, M., & Münch, M. (2018). Impact of long-term daylight deprivation on retinal light sensitivity, circadian rhythms and sleep during the Antarctic winter. Scientific Reports, 8, Article 16185. https://doi.org/10.1038/s41598-018-33450-7
Kealey, D. J. (2004). Research on intercultural effectiveness and its relevance to multicultural crews in space. Aviation, Space, and Environmental Medicine, 75(7, Suppl.), C58–C64.
Kim, J., Cifre, A., Bower, J. L., Connaboy, C., Simpson, R. J., & Alfano, C. A. (2022). Markers of distress among behavioral and physical health evacuees prior to emergency departure from Antarctica. Acta Astronautica, 202, 311–318. https://doi.org/10.1016/j.actaastro.2022.10.052
Klein, T., Braunsmann, L., Koschate, J., Hoffmann, U., Foitschik, T., Krieger, S., Crucian, B., Schneider, S., & Abeln, V. (2023). Short-term isolation effects on the brain, cognitive performance, and sleep: The role of exercise. Frontiers in Physiology, 14, Article 903072. https://doi.org/10.3389/fphys.2023.903072
Kuwabara, T., Naruiwa, N., Kawabe, T., Kato, N., Sasaki, A., Ikeda, A., Otani, S., Imura, S., Watanabe, K., & Ohno, G. (2021). Human change and adaptation in Antarctica: Psychological research on Antarctic wintering-over at Syowa Station. International Journal of Circumpolar Health, 80(1), 1886704. https://doi.org/10.1080/22423982.2021.1886704
La Torre, G. G., Groemer, G., Diaz-Artiles, A., Pattyn, N., Van Cutsem, J., Musilova, M., Kopeć, W., Schneider, S., Abeln, V., Larose, T. L., Ferlazzo, F., Zivi, P., de Carvalho, A. M., Sandal, G. M., Orzechowski, L., Nicolas, M., de Villemeur, R. B., du Traon, A. P., & Antunes, I. F. (2024). Space analogs and behavioral health performance research: Review and recommendations checklist from ESA Topical Team. npj Microgravity, 10, Article 98. https://doi.org/10.1038/s41526-024-00437-w
Landon, L. B., Douglas, G. L., Downs, M. E., Greene, M., Whitmire, A., Zwart, S. R., & Roma, P. G. (2019). The behavioral biology of teams: Multidisciplinary contributions to social dynamics in isolated, confined, and extreme environments. Frontiers in Psychology, 10, Article 2571. https://doi.org/10.3389/fpsyg.2019.02571
Landon, L. B., Miller, J. C. W., Bell, S. T., & Roma, P. G. (2024). When people start getting real: The Group Living Skills Survey for extreme work environments. Frontiers in Psychology, 15, Article 1348119. https://doi.org/10.3389/fpsyg.2024.1348119
Leach, J. (2016). Psychological factors in exceptional, extreme and torturous environments. Extreme Physiology & Medicine, 5, Article 7. https://doi.org/10.1186/s13728-016-0048-y
Lee, C. H., & Balint, T. S. (2021). Martian delight: Exploring qualitative contact for decoupled communications. Acta Astronautica, 193, 779–790. https://doi.org/10.1016/j.actaastro.2021.06.051
Li, H., Ding, Y., Zhao, B., Xu, Y., & Wei, W. (2023). Effects of immersion in a simulated natural environment on stress reduction and emotional arousal: A systematic review and meta-analysis. Frontiers in Psychology, 13, Article 1058177. https://doi.org/10.3389/fpsyg.2022.1058177
Márquez, J. J., Hillenius, S., Kanefsky, B., Zheng, J., Deliz, I., & Reagan, M. (2017). Increasing crew autonomy for long duration exploration missions: Self-scheduling. In 2017 IEEE Aerospace Conference (pp. 1–10). IEEE. https://doi.org/10.1109/AERO.2017.7943838
McPhee, J. C., & Charles, J. B. (2021). Human planetary and astrobiology exploration: How will radiation, low gravity, and isolated and confined conditions affect our health? Bulletin of the American Astronomical Society, 53(4). https://doi.org/10.3847/25c2cfeb.fa044931
Nicolas, M., Suedfeld, P., Weiss, K., & Gaudino, M. (2016). Affective, social, and cognitive outcomes during a 1-year wintering in Concordia. Environment and Behavior, 48(8), 1073–1091. https://doi.org/10.1177/0013916515583551
Nieuwenhuys, A., Dora, J., Knufinke-Meyfroyt, M., Beckers, D. G. J., Rietjens, G., & Helmhout, P. H. (2021). “20,000 leagues under the sea”: Sleep, cognitive performance, and self-reported recovery status during a 67-day military submarine mission. Applied Ergonomics, 91, 103295. https://doi.org/10.1016/j.apergo.2020.103295
Pagel, J. I., & Choukèr, A. (2016). Effects of isolation and confinement on humans: Implications for manned space explorations. Journal of Applied Physiology, 120(12), 1449–1457. https://doi.org/10.1152/japplphysiol.00928.2015
Pagnini, F., Manzey, D., Rosnet, É., Ferravante, D., White, O., & Smith, N. (2023). Human behavior and performance in deep space exploration: Next challenges and research gaps. npj Microgravity, 9, Article 27. https://doi.org/10.1038/s41526-023-00270-7
Palinkas, L. A., & Suedfeld, P. (2021). Psychosocial issues in isolated and confined extreme environments. Neuroscience & Biobehavioral Reviews, 126, 413–429. https://doi.org/10.1016/j.neubiorev.2021.03.032
Patel, Z. S., Brunstetter, T. J., Tarver, W. J., Whitmire, A. M., Zwart, S. R., Smith, S. M., & Huff, J. L. (2020). Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars. npj Microgravity, 6, Article 33. https://doi.org/10.1038/s41526-020-00124-6
Paulhus, D. L. (2017). Socially desirable responding on self-reports. In V. Zeigler-Hill & T. K. Shackelford (Eds.), Encyclopedia of personality and individual differences. Springer. https://doi.org/10.1007/978-3-319-28099-8_1349-1
Pei, G., Li, H., Lu, Y., Wang, Y., Hua, S., & Li, T. (2023). Affective computing: Recent advances, challenges, and future trends. Intelligent Computing, 3, Article 0076. https://doi.org/10.34133/icomputing.0076
Roma, P. G., & Bedwell, W. L. (2017). Key factors and threats to team dynamics in long-duration extreme environments. In E. Salas, W. B. Vessey, & L. B. Landon (Eds.), Team dynamics over time (Research on Managing Groups and Teams, Vol. 18, pp. 155–187). Emerald Publishing. https://doi.org/10.1108/S1534-085620160000018007
Roque, N., & Felt, J. M. (2025). Acceptability of active and passive data collection methods for mobile health research. JMIR Formative Research, 9, e64082. https://doi.org/10.2196/64082
Rosenberg, J. D., Jannasch, A., Binsted, K., & Landry, S. J. (2022). Biobehavioral and psychosocial stress changes during three 8–12 month spaceflight analog missions with Mars-like conditions of isolation and confinement. Frontiers in Physiology, 13, Article 898841. https://doi.org/10.3389/fphys.2022.898841
Rozanov, I. A., Ryumin, O., Karpova, O., Shved, D., Savinkina, A., Kuznetsova, P., Diaz Rey, N., Shishenina, K., & Gushin, V. (2022). Applications of methods of psychological support developed for astronauts for use in medical settings. Frontiers in Physiology, 13, Article 926597. https://doi.org/10.3389/fphys.2022.926597
Ru, T., Kompier, M. E., Chen, Q., Zhou, G., & Smolders, K. C. H. J. (2022). Temporal tuning of illuminance and spectrum: Effect of a full-day dynamic lighting pattern on well-being, performance and sleep in a simulated office environment. Building and Environment, 228, 109842. https://doi.org/10.1016/j.buildenv.2022.109842
Schlosser, K. K., Cinelli, I., Waelde, T., Álvarez, L. L., Pokorádi, G., Pósch, K., & Whiteley, I. (2025). Optimise behavioural health and human factors research for deep space missions by classifying analogue scenarios and fidelity. Frontiers in Space Technologies, 6, Article 1391331. https://doi.org/10.3389/frspt.2025.1391331
Sharp, J. L., Kelson, J., South, D., Saliba, A., & Kabir, M. A. (2025). Virtual reality and artificial intelligence as psychological countermeasures in space and other isolated and confined environments: A scoping review. Acta Astronautica, 232, 666–680. https://doi.org/10.1016/j.actaastro.2025.04.002
Shved, D., Kuznetsova, P., Rozanov, I. A., Lebedeva, S. A., Vinokhodova, A., Savinkina, A., Shishenina, K., Diaz Rey, N., & Gushin, V. (2022). Effects of isolation, crowding, and different psychological countermeasures on crew behavior and performance. Frontiers in Physiology, 13, Article 963301. https://doi.org/10.3389/fphys.2022.963301
Slavich, G. M., Taylor, S., & Picard, R. W. (2019). Stress measurement using speech: Recent advancements, validation issues, and ethical and privacy considerations. Stress, 22(4), 408–413. https://doi.org/10.1080/10253890.2019.1584180
Smith, N., Peters, D., Jay, C., Sandal, G. M., Barrett, E., & Wuebker, R. (2023). Off-world mental health: Considerations for the design of well-being-supportive technologies for deep space exploration. JMIR Formative Research, 7, e37784. https://doi.org/10.2196/37784
Spulber, S., Elberling, F., Svensson, J. E., Tiger, M., Ceccatelli, S., & Lundberg, J. (2022). Patterns of activity correlate with symptom severity in major depressive disorder patients. Translational Psychiatry, 12, Article 226. https://doi.org/10.1038/s41398-022-01989-9
Stahn, A. C., Bucher, D., zu Eulenburg, P., Denise, P., Smith, N., Pagnini, F., & White, O. (2023). Paving the way to better understand the effects of prolonged spaceflight on operational performance and its neural bases. npj Microgravity, 9, Article 59. https://doi.org/10.1038/s41526-023-00295-y
Stuster, J. (2010). Behavioral issues associated with long-duration space expeditions: Review and analysis of astronaut journals (NASA/CR-2010-216130). National Aeronautics and Space Administration. http://hdl.handle.net/2060/20100026549
Supolkina, N., Yusupova, A., Shved, D., Gushin, V., Savinkina, A., Lebedeva, S. A., Chekalina, A., & Kuznetsova, P. (2021). External communication of autonomous crews under simulation of interplanetary missions. Frontiers in Physiology, 12, Article 751170. https://doi.org/10.3389/fphys.2021.751170
Thomas, L. (2023). The future potential of virtual reality countermeasures for maintaining behavioural health during long-duration space exploration. Frontiers in Virtual Reality, 4, Article 1180165. https://doi.org/10.3389/frvir.2023.1180165
Trull, T. J., & Ebner-Priemer, U. W. (2013). Ambulatory assessment. Annual Review of Clinical Psychology, 9, 151–176. https://doi.org/10.1146/annurev-clinpsy-050212-185510
Van Puyvelde, M., Gijbels, D., Van Caelenberg, T., Smith, N., Bessone, L., Buckle-Charlesworth, S., & Pattyn, N. (2022). Living on the edge: How to prepare for it? Frontiers in Neuroergonomics, 3, Article 1007774. https://doi.org/10.3389/fnrgo.2022.1007774
Van Wijk, C. H. (2022). Psychological profiles of resilience in extreme environments: Correlating measures of personality and coping and resilience. Scientia Militaria: South African Journal of Military Studies, 50(1), 1–18. https://doi.org/10.5787/50-1-1256
Vigo, D. E., Tuerlinckx, F., Ogrinz, B., Wan, L., Simonelli, G., Bersenev, E. Y., den Bergh, O. V., & Aubert, A. E. (2013). Circadian rhythm of autonomic cardiovascular control during the Mars500 simulated mission to Mars. Aviation, Space, and Environmental Medicine, 84(10), 1023–1028. https://doi.org/10.3357/ASEM.3612.2013
Vitazkova, D., Svobodová, H., Turonova, D., Foltan, E., Jagelka, M., Berki, M., Micjan, M., Kokavec, O., Gerhat, F., & Vavrinský, E. (2025). Transforming sleep monitoring: Review of wearable and remote devices advancing home polysomnography and their role in predicting neurological disorders. Biosensors, 15(2), Article 117. https://doi.org/10.3390/bios15020117
Völker, J., Schlegel, K., & Mortillaro, M. (2025). Personality traits and cognitive abilities in conflict management: Preliminary insights from a situational judgment test of emotional intelligence. Journal of Intelligence, 13(11), Article 143. https://doi.org/10.3390/jintelligence13110143
Wang, Y., Jing, X., Lv, K., Wu, B., Bai, Y., Luo, Y., Chen, S., & Li, Y. (2014). During the long way to Mars: Effects of 520 days of confinement in the Mars500 experiment on the assessment of affective stimuli and stage alteration in mood and plasma hormone levels. PLOS ONE, 9(4), e87087. https://doi.org/10.1371/journal.pone.0087087
Woo, E., Sansing, L., Arnsten, A. F. T., & Datta, D. (2021). Chronic stress weakens connectivity in the prefrontal cortex: Architectural and molecular changes. Chronic Stress, 5, 24705470211029254. https://doi.org/10.1177/24705470211029254
Yin, Y., Liu, J., Fan, Q., Zhao, S., Wu, X., Wang, J., Liu, Y., Li, Y., & Lu, W. (2023). Long-term spaceflight composite stress induces depression and cognitive impairment in astronauts: Insights from neuroplasticity. Translational Psychiatry, 13, Article 342. https://doi.org/10.1038/s41398-023-02638-5
Yuan, M., Custaud, M.-A., Xu, Z., Wang, J., Yuan, M., Tafforin, C., Treffel, L., Arbeille, P., Nicolas, M., Gharib, C., Gauquelin-Koch, G., Laurent, A., Lloret, J.-C., Li, Y., & Navasiolava, N. (2019). Multi-system adaptation to confinement during the 180-day Controlled Ecological Life Support System experiment. Frontiers in Physiology, 10, Article 575. https://doi.org/10.3389/fphys.2019.00575
Zhou, D., Luo, J., Silenzio, V., Zhou, Y., Hu, J., Currier, G. W., & Kautz, H. (2015). Tackling mental health by integrating unobtrusive multimodal sensing. Proceedings of the AAAI Conference on Artificial Intelligence, 29(1), 1401–1407. https://doi.org/10.1609/aaai.v29i1.9381
Zimmermann, S., Klusmann, D., & Hampe, W. (2017). Correcting the predictive validity of a selection test for the effect of indirect range restriction. BMC Medical Education, 17, Article 246. https://doi.org/10.1186/s12909-017-1070-5
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